At Silantes, we are experts in incorporating simple, inorganic stable isotope labeled molecules into complex organic molecules such as amino acids, peptides, proteins, nucleotides, RNA and DNA.
Our custom RNA and DNA synthesis services provide researchers and scientists with the ability to obtain tailor-made nucleic acid molecules with specific sequences, modifications, and labels.
These services can be implemented across a wide range of research applications.
Sequence Design and Synthesis
Silantes offers the flexibility to design and synthesize nucleic acid molecules with desired sequences, lengths, and complexity. This includes the synthesis of oligonucleotides, small interfering RNAs (siRNAs), messenger RNAs (mRNAs), long non-coding RNAs (lncRNAs), gene constructs, and more. Researchers can specify the exact nucleotide sequence they require, ensuring a high degree of precision and accuracy.
We provide many custom synthesis services that allow you to incorporate a wide range of chemical modifications into the nucleic acid molecules. Common modifications include methylated bases, fluorescent labels, biotin, phosphorothioate linkages, and locked nucleic acids (LNAs). These modifications can enhance the stability, specificity, and functionality of the synthesized nucleic acids.
Stable Isotope Labeling
Our custom synthesis services can also produce stable isotope-labeled nucleic acids using isotopes such as 2H, 13C, and 15N. These labels are valuable for structural and functional studies, allowing researchers to gain insights into the dynamics, interactions, and behavior of nucleic acids.
Scale and Purification
We can synthesize nucleic acid at different scales, ranging from small-scale research quantities to large-scale production for clinical and industrial applications, through our custom synthesis services. Additionally, Silantes can provide synthesized nucleic acids with varying levels of purification, including desalting, high-performance liquid chromatography (HPLC), and polyacrylamide gel electrophoresis (PAGE).
For researchers and industry professionals interested in harnessing the power of custom RNA/DNA synthesis and stable isotope labeling, we invite you to take the next steps in accessing these services. Whether you have a specific research project in mind or are simply curious about the possibilities, we encourage you to reach out for more information and explore the services available to you.
At Silantes, we specialize in producing a wide range of stable isotope labeled molecules.
We are excited to offer you a product line that is truly unrivaled in the industry, whether you need isotope-labeled RNA and DNA building blocks (NTPs and phosphoramidites) or top-notch services for oligonucleotide synthesis.
For RNA and DNA technology products and services, our existing customers choose us because:
- we are uniquely equipped to produce a range of labeling that ensures high purity, and lower costs than our competitors
- of our extensive knowledge of the special requirements for handling stable isotope-labeled reagents in oligonucleotide synthesis
- of our ability to provide optimization of oligonucleotide synthesis services with respect to minimal use of stable isotopes and small sample sizes.
For researchers and industry professionals interested in harnessing the power of custom RNA/DNA synthesis and stable isotope labeling, we invite you to take the next steps in accessing these services.
Whether you have a specific research project in mind or are simply curious about the possibilities, we encourage you to contact us for more information and explore the services available to you.
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